"Among the thousands of migrants who are detained by states each year, those who are perhaps most vulnerable to human rights violations are oftentimes invisible within the immigration systems: LGBTI detainees. Human rights violations perpetrated against these individuals, who may be targeted during their detention as a result of their sexual orientation or gender identity, are made all the more egregious since many LGBTI detainees in immigration detention chose to migrate from their countries of origin as a result of persecution faced specifically due to their sexual orientation or gender identity." This article covers: the detention of irregular migrants and effects on LGBTI populations-factors contributing to LGBTI migration, expanding practice of immigration detention, and international human rights law and immigration detention; identification of LGBTI migrants; and specific protection gaps faced by LGBTI migrants-physical violence, sexual abuse, and aftereffects of violence, social isolation and segregation, barriers to medical care, and the high degree of trauma-related mental health issues.